Purinethol belongs to the group of medications known as antineoplastics. It fights cancer by preventing the growth of cancer cells, which eventually results in their destruction. This medication is used with other drugs to treat a certain type of cancer (acute lymphocytic leukemia). This drug may also be used to treat Crohn's disease, ulcerative colitis, and lymphoblastic lymphoma.
Take Purinethol exactly as prescribed by your doctor. Take this medication by mouth with or without food with a full glass of water, usually once daily. Drink plenty of fluids while taking this medication to decrease the risk of side effects. A typical starting dose for adults is between 100 mg and 200 mg daily, while an average 5 year old child could typically start on a dose of 50 mg daily.
Before taking Purinethol you should talk with your doctor if you have blood disorders, anemia, low blood cell counts, gout, kidney disease, kidney stones, liver disease, pancreatitis, radiation treatment, cancer, lymphoma. Do not have immunizations or vaccinations. Avoid being near people who have colds, the flu, or other contagious illnesses. Limit alcoholic beverages. Alcohol may increase the risk of stomach or esophageal irritation or liver damage. The elderly may be more sensitive to the effects of the drug.
Do not take Purinethol if you are allergic to mercaptopurine or any ingredients of this medication, are pregnant or breastfeeding.
Possible side effect
Get emergency medical help if you have darkening of skin, diarrhea, headache, nausea, vomiting, skin rash, itching, weakness, joint pain, swelling of feet, unusual tiredness, weakness, yellow eyes or skin, black or bloody stools, cough, hoarseness, fever, chills, lower back pain, painful or difficult urination, unusual bleeding, bruising, sore throat, body aches, loss of appetite, dark urine, hair loss, upset stomach, swelling of your face, lips, tongue, hives, difficulty breathing. If you notice other effects not listed above, contact your doctor.
Tell your doctor about all other medications you use, especially: allopurinol, thioguanine, olsalazine, azathioprine, blood thinners (warfarin), trimethoprim, cyclosporine, sulfasalazine, aspirin, erythromycin, amiodarone. Interaction between two medications does not always mean that you must stop taking one of them. Tell your doctor or prescriber about all prescription, over-the-counter, and herbal medications you are taking.
Take the missed dose as soon as possible. Skip the missed dose if it is time for your next scheduled dose. Don't take extra medicine to make up the missed dose.
If you think you have overdosed the medicine seek emergency medical help at once. The overdose symptoms are yellowing of the eyes or skin, nausea, diarrhea, emesis, dark urine, severe abdominal pain.
Store the medicine at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store the drugs in the bathroom. Keep all drugs away from reach of children and pets.
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