Prometrium is a female hormone important for the regulation of ovulation and menstruation. It contains the hormone progesterone. It is used to cause menstrual periods in women who have not yet reached menopause but are not having periods due to a lack of progesterone in the body. Progesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.
Use Prometrium exactly as it was prescribed for you. It is sometimes given for only a short period of time, such as 6 to 12 days at a time during each menstrual cycle. Take the pill with a full glass of water with or without food. The recommended dose of progesterone is 200 mg daily taken at bedtime for the last 14 days of estrogen treatment per cycle. You may not have regular periods while taking Prometrium.
Talk with your doctor prior to using Prometrium if you have: epilepsy, asthma, heart problems, cancer, high blood pressure, diabetes, cirrhosis, hepatitis, migraines, unexplained vaginal bleeding. Progesterone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Do not take this medication if you are allergic to progesterone, peanuts, or any ingredients of Prometrium, are pregnant or breastfeeding, if you have liver disease, heart disease, endometrial hyperplasia, breast or endometrial cancer.
Possible side effect
Common side effects are: dizziness, abdominal (stomach) pain, headaches, breast pain, muscle pain, nausea, vomiting, diarrhea, coughing, back pain, fatigue, hot flashes, blood pressure increase, trouble sleeping, mood changes. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Tell your doctor about all other medicines you use, especially: modafinil, aminoglutethimide, antibiotics, antifungal medications, barbiturate medications (secobarbital, phenobarbital, primidone), ketoconazole, rifampin, topotecan. Interaction between two medications does not always mean that you must stop taking one of them. Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking.
Take the missed dose as soon as possible. Skip the missed dose if it is time for your next scheduled dose. Don't take extra medicine to make up the missed dose.
If you think you have overdosed the medicine seek emergency medical help at once. The overdose symptoms are bloating, jaundice, breast pain, headaches, irregular menstrual periods, dizziness, decreased sex drive, depression.
Store the medicine at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store the drugs in the bathroom. Keep all drugs away from reach of children and pets.
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